Description:
Pleconaril is a capsid function inhibitor which targets a conserved hydrophobic pocket of a major viral capsid protein called VP-1. Pleconaril inhibits attachment and virus uncoating.
- Molecular Weight: 381.35
- Molecular Formula: C18H18F3N3O3
Purity: 0.9996
Canonical SMILES:
CC1=CC(=CC(=C1OCCCC2=CC(=NO2)C)C)C3=NOC(=N3)C(F)(F)F
InChI:
1S/C18H18F3N3O3/c1-10-7-13(16-22-17(27-24-16)18(19,20)21)8-11(2)15(10)25-6-4-5-14-9-12(3)23-26-14/h7-9H,4-6H2,1-3H
InChIKey: KQOXLKOJHVFTRN-UHFFFAOYSA-N
- Boiling Point: 481.2±55.0 °C | Condition: Press: 760 Torr
- Melting Point: 61-62°
- Solubility: Soluble in DMSO
- Appearance: Off-White solid
- Application: Picornavirus replication inhibitor. Antiviral.
- Storage: Store in a cool and dry place and at 0 - 4°C for short term (days to weeks) or -64°C for long term (months to years).
Synonyms:
SR-263843; SR-63843; VP-63843; Win-63843; SR263843; SR63843; VP63843; Win63843; SR 263843; SR 63843; VP 63843; Win 63843; Pleconaril, Picovir. 3-[3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole3-(3,5-dimethyl-4((3-(3-methyl-5-isoxazolyl)propyl)phenyl)-5-trifluoromethyl)-1,2,4-oxadiazolePicovirpleconaril
More details are to be found on supplier website
