Description:
SB 203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM, also blocks PKB phosphorylation with IC50 of 3-5 μM.
- Molecular Weight: 377.437
- Molecular Formula: C21H16FN3OS
Purity: >98%
Canonical SMILES:
CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F
InChI:
InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)
InChIKey: CDMGBJANTYXAIV-UHFFFAOYSA-N
- Boiling Point: 615.6±55.0 °C at 760 mmHg
- Melting Point: 249-250°C
- Application: Enzyme Inhibitors
Synonyms:
SB203580; SB203580; SB 203580
More details are to be found on supplier website
