Description:
(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent.
- Molecular Weight: 381.54
- Molecular Formula: C22H27NO3Si
Purity: 98%
Canonical SMILES:
CC[Si](CC)(CC)OC1C(N(C1=O)C(=O)C2=CC=CC=C2)C3=CC=CC=C3
InChI:
InChI=1S/C22H27NO3Si/c1-4-27(5-2,6-3)26-20-19(17-13-9-7-10-14-17)23(22(20)25)21(24)18-15-11-8-12-16-18/h7-16,19-20H,4-6H2,1-3H3/t19-,20+/m0/s1
InChIKey: PMFXBVOLZORTNG-VQTJNVASSA-N
- Boiling Point: 467.2±55.0 °C (Predicted)
- Solubility: Soluble in Dichloromethane, Ether, Ethyl Acetate, Methanol
- Appearance: Transparent Oil
- Storage: -20 °C
Synonyms:
(+)-cis-1-Benzoyl-3-triethylsilyloxy-4-phenyl-2-azetidinone; 1-Benzoyl-3alpha-(triethylsiloxy)-4alpha-phenylazetidin-2-one; N-benzoyl-3-triethylsilyloxy-4-phenylazetidin-2-one
More details are to be found on supplier website
