Description:
Delavirdine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It is used as part of highly active antiretroviral therapy (HAART) for the treatment of human immunodeficiency virus (HIV) type 1.
- Molecular Weight: 552.67
- Molecular Formula: C23H32N6O6S2
Purity: >98%
Canonical SMILES:
CC(C)NC1=C(N=CC=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)NS(=O)(=O)C.CS(=O)(=O)O
InChI:
InChI=1S/C22H28N6O3S.CH4O3S/c1-15(2)24-19-5-4-8-23-21(19)27-9-11-28(12-10-27)22(29)20-14-16-13-17(26-32(3,30)31)6-7-18(16)25-20;1-5(2,3)4/h4-8,13-15,24-26H,9-12H2,1-3H3;1H3,(H,2,3,4)
InChIKey: MEPNHSOMXMALDZ-UHFFFAOYSA-N
- Boiling Point: 732°C at 760mmHg
- Melting Point: 118-120°C
- Solubility: In Vitro: DMSO : ≥ 40.3 mg/mL(72.92 mM)In Vivo: 1.Add each solvent one by one: 10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% salineSolubility: ≥ 2.5 mg/mL (4.52 mM); Clear solution2.Add each solvent one by one: 10% DMSO >> 90% (20%SBE-β-CDin saline)Solubility: ≥ 2.5 mg/mL (4.52 mM); Clear solution3.Add each solvent one by one: 10% DMSO >> 90%corn oilSolubility: ≥ 2.5 mg/mL (4.52 mM); Clear solution
- Appearance: White to yellow (Solid)
- Application: Anti-HIV Agents
- Storage: 4°C, sealed storage, away from moisture* In solvent : -80°C, 6 months-20°C, 1 month (sealed storage, away from moisture)
Synonyms:
Delavirdine mesylate; Rescriptor; U-90152S; U 90152S; U90152S; U 90152T U-90152T; U90152T; U 90152E; U-90152E; U90152E;
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