Description:
Tiagabine hydrochloride is an anticonvulsant and selective GABA reuptake inhibitor through inhibition of the synaptic GABA transporter GAT1. Tiagabine increases the synaptic GABA and enhances the neuronal inhibition. It is effective as adjunctive treatment of epilepsy and anxiety disorders.
- Molecular Weight: 412.01
- Molecular Formula: C20H26ClNO2S2
Purity: >98%
Canonical SMILES:
CC1=C(SC=C1)C(=CCCN2CCCC(C2)C(=O)O)C3=C(C=CS3)C.Cl
InChI:
InChI=1S/C20H25NO2S2.ClH/c1-14-7-11-24-18(14)17(19-15(2)8-12-25-19)6-4-10-21-9-3-5-16(13-21)20(22)23;/h6-8,11-12,16H,3-5,9-10,13H2,1-2H3,(H,22,23);1H/t16-;/m1./s1
InChIKey: YUKARLAABCGMCN-PKLMIRHRSA-N
- Melting Point: >186°C (dec.)
- Appearance: Off-White to Pale Beige Solid
Synonyms:
Gabitril hydrochloride; NO050328 hydrochloride; NO328 hydrochloride; NO-050328 hydrochloride; NO 328 hydrochloride; NO O050328 hydrochloride; NO 328 hydrochloride; TGB hydrochloride
More details are to be found on supplier website
