Description:
Vinblastine sulfate, also called cellblastin, derived from C. roseus, as a microtubule disrupter and antineoplastic agent, it binds tubulin and disrupts microtubule assembly and proper formation of the mitotic spindle, which leads to the assembly of microtubules and causing M phase-specific cell cycle arrest.
- Molecular Weight: 909.06
- Molecular Formula: C46H58N4O9.H2SO4
Purity: >98%
Canonical SMILES:
CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O
InChI:
1S/C46H58N4O9.H2O4S/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7;1-5(2,3)4/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3;(H2,1,2,3,4)
InChIKey: KDQAABAKXDWYSZ-UHFFFAOYSA-N
- Melting Point: 267°C
- Solubility: Soluble to 100 mM in water and to 100 mM in DMSO
- Appearance: Solid powder
- Application: anticancer
- Storage: Store in a cool and dry place and at 0 - 4°C for short term (days to weeks) or -67°C for long term (months to years).
Synonyms:
cell pharm Brand of Vinblastine Sulfate; cellblastin; EG Labo Brand of Vinblastine Sulfate; Faulding Brand of Vinblastine Sulfate; Gastrozepin Brand of Vinblastine Sulfate; Gry Brand of Vinblastine Sulfate; Hexal Brand of Vinblastine Sulfate; Lemblastine; Lemery Brand of Vinblastine Sulfate; Lilly Brand of Vinblastine Sulfate; Sulfate, Vinblastine; Velban; Velbe; Vinblastin Hexal; Vinblastina Lilly; Vinblastine; Vinblastine Sulfate; Vinblastinsulfat-Gry; Vincaleukoblastine; Vinblastine sulfate; 143-67-9; C46H58N4O9H2SO4
More details are to be found on supplier website
