Description:
E7046 is an orally bioavailable and specific type 4 prostaglandin E2 (PGE2) receptor EP antagonist (IC50= 13.5 nM) (Ki= 23.14 nM), with anti-tumor activities.
- Molecular Weight: 483.39
- Molecular Formula: C22H18F5N3O4
Canonical SMILES:
CC(C1=CC=C(C=C1)C(=O)O)NC(=O)C2=C(N(N=C2C(F)F)C)OC3=CC=CC(=C3)C(F)(F)F
InChI:
1S/C22H18F5N3O4/c1-11(12-6-8-13(9-7-12)21(32)33)28-19(31)16-17(18(23)24)29-30(2)20(16)34-15-5-3-4-14(10-15)22(25,26)27/h3-11,18H,1-2H3,(H,28,31)(H,32,33)/t11-/m0/s1
InChIKey: MKLKAQMPKHNQPR-NSHDSACASA-N- Boiling Point: 594.8±50.0 °C at 760 Torr
- Solubility: DMSO: ≥ 100 mg/mL
- Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms:
E7046; E-7046; E 7046. 4-[(1S)-1-[[3-(difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]pyrazole-4-carbonyl]amino]ethyl]benzoic acid
More details are to be found on supplier website
