Description:
Minocycline (INN) is a semi-synthetic broad-spectrum tetracycline antibiotic. Minocycline hydrochloride is the most lipid-soluble form, which binds to the 30S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis. In combination with CHIR 99021, (S)-(+)-Dimethindene maleate and human leukemia inhibitory factor, it induces the formation of extended pluripotent stem (EPS) cells.
- Molecular Weight: 493.94
- Molecular Formula: C23H27N3O7.HCl
Purity: Assay 96.0%-102.5%
Canonical SMILES:
CN(C)C1C2CC3CC4=C(C=CC(=C4C(=C3C(=O)C2(C(=C(C1=O)C(=O)N)O)O)O)O)N(C)C.Cl
InChI:
InChI=1S/C23H27N3O7.ClH/c1-25(2)12-5-6-13(27)15-10(12)7-9-8-11-17(26(3)4)19(29)16(22(24)32)21(31)23(11,33)20(30)14(9)18(15)28;/h5-6,9,11,17,27-28,31,33H,7-8H2,1-4H3,(H2,24,32);1H/t9-,11-,17-,23-;/m0./s1
InChIKey: WTJXVDPDEQKTCV-VQAITOIOSA-N
- Boiling Point: 659.4°C at 760 mmHg
- Melting Point: 205-210°C (dec)
- Solubility: Soluble in ethanol, methanol, DMF, DMSO
- Appearance: Yellow Crystalline Powder
- Storage: Preserve in tight containers, protected from light
Synonyms:
Minocycline HCl; Arestin; Minomycin
More details are to be found on supplier website
