Description:
Koumine has a significant analgesic effect in rodent behavioral models of inflammatory and neuropathic pain, and that the reduction in neuropathic pain may be associated with the upregulation of allopregnanolone in the spinal cord. Koumine has the potential to be a future breast cancer chemotherapeutic agent.
- Molecular Weight: 306.4
- Molecular Formula: C20H22N2O
Purity: >98%
Canonical SMILES:
CN1CC2(C3CC4C5=NC6=CC=CC=C6C52CC1C3CO4)C=C
InChI:
InChI=1S/C20H22N2O/c1-3-19-11-22(2)16-9-20(19)13-6-4-5-7-15(13)21-18(20)17-8-14(19)12(16)10-23-17/h3-7,12,14,16-17H,1,8-11H2,2H3/t12-,14+,16-,17+,19-,20+/m0/s1
InChIKey: VTLYEMHGPMGUOT-FXWNUWCSSA-N
- Boiling Point: 436.5±45.0°C (Predicted)
- Melting Point: 168°C
- Appearance: Powder
- Application: Antineoplastic
- Storage: 2-8°C
Synonyms:
(3R,7alpha,20alpha)-1,2,18,19-Tetradehydro-3,17-epoxy-7,20(2H,19H)cyclovobasan; 7,20(2H,19H)-Cyclovobasan, 1,2,18,19-tetradehydro-3,17-epoxy-, (3R,7alpha,20alpha)-
More details are to be found on supplier website
