Description:
ML241 is a selective p97 ATPase inhibitor and IC50 value is 100 nM. It can inhibit degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-reporter cell line. ML241 may be a novel agent for the treatment of cancer.
- Molecular Weight: 372.46
- Molecular Formula: C23H24N4O
Purity: 98%
Canonical SMILES:
C1(N2CCOC3=CC=CC=C23)=NC(NCC4=CC=CC=C4)=C5CCCCC5=N1
InChI:
1S/C23H24N4O/c1-2-8-17(9-3-1)16-24-22-18-10-4-5-11-19(18)25-23(26-22)27-14-15-28-21-13-7-6-12-20(21)27/h1-3,6-9,12-13H,4-5,10-11,14-16H2,(H,24,25,26)
InChIKey: RMZPVQQGYVSLAP-UHFFFAOYSA-N
- Solubility: Soluble in DMSO
- Appearance: Solid powder
- Application: anticancer
- Storage: -20°C Freezer
Synonyms:
2-(2H-benzo[b][1,4]oxazin-4(3H)-yl)-N-benzyl-5,6,7,8-tetrahydroquinazolin-4-amine; ML241; ML-241; ML 241
More details are to be found on supplier website
