Description:
Tyrphostin AG490 is a JAK-2 specific inhibitor, which inhibits phosphorylation of EGFR and signal transducer and activator of transcription 3 [STAT-3], and subsequently reduce invasion and adhesion potential of malignant cells.
- Molecular Weight: 294.31
- Molecular Formula: C17H14N2O3
Purity: 0.98
Canonical SMILES:
C1=CC=C(C=C1)CNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
InChI:
InChI=1S/C17H14N2O3/c18-10-14(8-13-6-7-15(20)16(21)9-13)17(22)19-11-12-4-2-1-3-5-12/h1-9,20-21H,11H2,(H,19,22)/b14-8+
InChIKey: TUCIOBMMDDOEMM-RIYZIHGNSA-N
- Appearance: Light yellow to yellow Solid
- Application: Antineoplastic Agents
Synonyms:
Tyrphostin AG 490; AG-490; AG490
More details are to be found on supplier website
