Description:
TMP269 is a highly potent, selective and cell-permeable class IIa HDAC inhibitor with IC50 values of 126 nM, 80 nM, 36 nM and 19 nM for HDAC4, HDAC5, HDAC7 and HDAC9 respectively.
- Molecular Weight: 514.523
- Molecular Formula: C25H21F3N4O3S
Purity: 98%
Canonical SMILES:
C1COCCC1(CNC(=O)C2=CC=CC(=C2)C3=NOC(=N3)C(F)(F)F)C4=NC(=CS4)C5=CC=CC=C5
InChI:
InChI=1S/C25H21F3N4O3S/c26-25(27,28)22-31-20(32-35-22)17-7-4-8-18(13-17)21(33)29-15-24(9-11-34-12-10-24)23-30-19(14-36-23)16-5-2-1-3-6-16/h1-8,13-14H,9-12,15H2,(H,29,33)
InChIKey: HORXBWNTEDOVKN-UHFFFAOYSA-N
- Appearance: White to Off-white Solid Powder
Synonyms:
TMP269; TMP 269; TMP-269; N-((4-(4-Phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide
More details are to be found on supplier website
