Description:
HS-173 is a potent and selective PI3Kα inhibitor displaying anticancer activity. HS-173 was shown to induce apoptosis via arresting the cell cycle at the G2/M phase. It also decreases angiogenesis induced by VEGF.
- Molecular Weight: 422.459
- Molecular Formula: C21H18N4O4S
Purity: 98%
Canonical SMILES:
CCOC(=O)C1=CN=C2N1C=C(C=C2)C3=CC(=CN=C3)NS(=O)(=O)C4=CC=CC=C4
InChI:
InChI=1S/C21H18N4O4S/c1-2-29-21(26)19-13-23-20-9-8-15(14-25(19)20)16-10-17(12-22-11-16)24-30(27,28)18-6-4-3-5-7-18/h3-14,24H,2H2,1H3
InChIKey: SEKOTFCHZNXZMM-UHFFFAOYSA-N
- Melting Point: >193°C (dec.)
- Appearance: Grey to Brown Solid
Synonyms:
Ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate; HS173; HS 173; HS-173.
More details are to be found on supplier website
