Description:
OG (Olumacostat glasaretil) is a acetyl-coenzyme A carboxylase inhibitor. Acetyl-COA carboxylase is the key point for the first, rate-limiting step in de novo fatty acid synthesis. OG can inhibit in vitro human sebocyte lipid production, it can also reduce in vivo sebaceous gland size in hamster ears.
- Molecular Weight: 481.63
- Molecular Formula: C26H43NO7
Purity: 98%
Canonical SMILES:
CCCCCCCCCCCCCCOc1oc(cc1)C(=O)OCC(=O)N(C)CC(=O)OCC
InChI:
1S/C26H43NO7/c1-4-6-7-8-9-10-11-12-13-14-15-16-19-32-25-18-17-22(34-25)26(30)33-21-23(28)27(3)20-24(29)31-5-2/h17-18H,4-16,19-21H2,1-3H3
InChIKey: FYJLDICZGDFWKP-UHFFFAOYSA-N
- Solubility: Soluble in DMSO
- Appearance: Powder
- Storage: -20°C Freezer
Synonyms:
Olumacostat glasaretil; DRM01B; DRM-01B; DRM 01B. 2-((2-ethoxy-2-oxoethyl)(methyl)amino)-2-oxoethyl 5-(tetradecyloxy)furan-2-carboxylate
More details are to be found on supplier website