Description:
The hydrochloride salt form of Rotigotine which is a dopamine D2 and D3 receptor agonist and has been shown to be effective in the treatment of Parkinson's disease. IC50: 13 nM and 0.71 nM for D2 and D3 receptor respectively.
- Molecular Weight: 351.93
- Molecular Formula: C19H26ClNOS
Purity: >99 %
Canonical SMILES:
CCCN(CCC1=CC=CS1)C2CCC3=C(C2)C=CC=C3O.Cl
InChI:
InChI=1S/C19H25NOS.ClH/c1-2-11-20(12-10-17-6-4-13-22-17)16-8-9-18-15(14-16)5-3-7-19(18)21;/h3-7,13,16,21H,2,8-12,14H2,1H3;1H/t16-;/m0./s1
InChIKey: CEXBONHIOKGWNU-NTISSMGPSA-N
- Solubility: 10 mM in water ; 100 mM in DMSO
- Appearance: White crystalline powder
- Application: The hydrochloride salt form of Rotigotine which is a dopamine D2 and D3 receptor agonist and has been shown to be effective in the treatment of Parkinson's disease.
- Storage: -20°C Freeze
Synonyms:
Rotigotine hydrochloride; Rotigotine HCl; Rotigotine (Hydrochloride); (S)-6-(Propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride; (6S)-6-[propyl(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride
More details are to be found on supplier website
