Description:
Tenofovir soproxil carbamate analog is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS.
- Molecular Weight: 489.43
- Molecular Formula: C18H28N5O9P
Purity: ≥95%
Canonical SMILES:
CC(C)OC(=O)NC1=C2C(=NC=N1)N(C=N2)CC(C)OCP(=O)(O)OCOC(=O)OC(C)C
InChI:
InChI=1S/C18H28N5O9P/c1-11(2)31-17(24)22-15-14-16(20-7-19-15)23(8-21-14)6-13(5)29-10-33(26,27)30-9-28-18(25)32-12(3)4/h7-8,11-13H,6,9-10H2,1-5H3,(H,26,27)(H,19,20,22,24)/t13-/m1/s1
InChIKey: CEFDJALYGKEXAQ-CYBMUJFWSA-N
- Melting Point: >113°C (dec.)
- Solubility: Soluble in Methanol
- Appearance: White to Off-White Solid
- Storage: Store at -20°C
Synonyms:
O-Isopropoxycarbonyloxymethyl hydrogen (R)-[1-[(6-isopropoxycarbonylamino)-9H-purin-9-yl]propan-2-yloxy]methylphosphonate; Isopropyl (9-((2R)-2-((hydroxy(((isopropoxycarbonyl)oxy)methoxy)phosphoryl)methoxy)propyl)-9H-purin-6-yl)carbamate; Mono-POC Tenofovir 6-Isopropyl Carbamate; (8R)-9-(6-Isopropylaminocarbamate-9H-purin-9-yl)-5-hydroxy-8-methyl-2,4,7-trioxa-5-phosphanonanoic Acid 1-Methylethyl Ester 5-Oxide; Tenofovir Disoproxil Fumarate IP Impurity E; Tenofovir Impurity E; (1-methylethyl) (8R)-5-hydroxy-8-methyl-9-(6-{[(1-methylethoxy)carbonyl]amino}-9H-purin-9-yl)-5-oxo-2,4,7-trioxa-5-λ5-phosphanonanoate
More details are to be found on supplier website
