Description:
AVL-292, also known as CC-292, is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic activity. Upon administration, AVL-292 targets and covalently binds to BTK, thereby preventing its activity.
- Molecular Weight: 423.44
- Molecular Formula: C22H22FN5O3
Purity: 98%
Canonical SMILES:
COCCOC1=CC=C(C=C1)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)NC(=O)C=C)F
InChI:
InChI=1S/C22H22FN5O3/c1-3-20(29)25-16-5-4-6-17(13-16)26-21-19(23)14-24-22(28-21)27-15-7-9-18(10-8-15)31-12-11-30-2/h3-10,13-14H,1,11-12H2,2H3,(H,25,29)(H2,24,26,27,28)
InChIKey: KXBDTLQSDKGAEB-UHFFFAOYSA-N
- Appearance: white solid powder
- Application: Protein Kinase Inhibitors
Synonyms:
CC-292; CC292; CC 292; AVL292; AVL 292; spebrutinib
More details are to be found on supplier website
