Description:
CPI-444 is a potent, orally available, selective antagonist of the adenosine A2A receptor that has been well tolerated in Ph 1/1b studies in non-oncology indications.
- Molecular Weight: 407.17
- Molecular Formula: C20H21N7O3
Canonical SMILES:
NC1=NC2=C(N=NN2CC3=NC(CO[C@H]4CCOC4)=CC=C3)C(C5=CC=C(O5)C)=N1
InChI:
1S/C20H21N7O3/c1-12-5-6-16(30-12)17-18-19(24-20(21)23-17)27(26-25-18)9-13-3-2-4-14(22-13)10-29-15-7-8-28-11-15/h2-6,15H,7-11H2,1H3,(H2,21,23,24)/t15-/m0/s1
InChIKey: KURQKNMKCGYWRJ-HNNXBMFYSA-N- Boiling Point: 676.9±65.0 °C at 760 Torr
- Solubility: DMSO
- Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms:
(S)-7-(5-methylfuran-2-yl)-3-((6-(((tetrahydrofuran-3-yl)oxy)methyl)pyridin-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine; CPI-444; CPI 444; CPI444; V81444; V-81444; V 81444
More details are to be found on supplier website
