Description:
Donepezil is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM , respectively.
- Molecular Weight: 415.95
- Molecular Formula: C24H30ClNO3
Purity: ≥ 95%
Canonical SMILES:
COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC.Cl
InChI:
InChI=1S/C24H29NO3.ClH/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18;/h3-7,14-15,17,20H,8-13,16H2,1-2H3;1H
InChIKey: XWAIAVWHZJNZQQ-UHFFFAOYSA-N
- Boiling Point: 527.9 °C at 760 mmHg
- Melting Point: 220-222 °C (dec.)
- Solubility: Slightly soluble in DMSO, Methanol, Water
- Appearance: White to Off-white Solid
- Application: Cholinesterase Inhibitors
- Storage: -20 °C under inert atmosphere
Synonyms:
2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-oneHydrochloride; Aricept; Aricept D; BNAG; Donepezil HCl; BNAG; donepezilium oxalate trihydrate; 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride
More details are to be found on supplier website
