Description:
Combretastatin A4 is a stilbenoid isolated from Combretum caffrum. Combretastatin A4 was shown to inhibit tubulin polymerization (IC50 = 2.2 μM). It has demonstrable antineoplastic activity.
- Molecular Weight: 316.35
- Molecular Formula: C18H20O5
Purity: ≥95%
Canonical SMILES:
COC1=C(C=C(C=C1)C=CC2=CC(=C(C(=C2)OC)OC)OC)O
InChI:
InChI=1S/C18H20O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11,19H,1-4H3/b6-5-
InChIKey: HVXBOLULGPECHP-WAYWQWQTSA-N
- Melting Point: 84.5-85.5°C
- Solubility: Soluble to 100 mm in ethanol and to 100 mm in DMSO
- Appearance: White to off-white powder
- Application: Antineoplastic Agents, Phytogenic
- Storage: - 20 °C
Synonyms:
1-(3,4,5-trimethoxyphenyl)-2-(3'-hydroxy-4'-methoxyphenyl)ethene
More details are to be found on supplier website
