Description:
EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE).
- Molecular Weight: 299.76
- Molecular Formula: C11H18ClN7O
Purity: ≥98% by HPLC
Canonical SMILES:
CCN(C1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N)C(C)C
InChI:
InChI=1S/C11H18ClN7O/c1-4-19(5(2)3)9-7(12)16-6(8(13)17-9)10(20)18-11(14)15/h5H,4H2,1-3H3,(H2,13,17)(H4,14,15,18,20)
InChIKey: QDERNBXNXJCIQK-UHFFFAOYSA-N
- Melting Point: 198-200°C
- Appearance: Light Yellow to Light Green Solid
- Application: Epithelial Sodium Channel Blockers
Synonyms:
Ethylisopropylamiloride; L 593754; MH 12-43; 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide
More details are to be found on supplier website
