Description:
Lansiumarin C is a natural coumarin found in the branches of Clausena lansium. and found to induce senescence of cancer cell lines, it induces growth arrest of cancer cell lines HepG2, Huh7 and K562; activation of the mitogen-activated protein kinase EKR and up-regulation of cyclin-dependent kinase inhibitor p16 were found in early stages of Ganoderiol F treatment and were presumed to cause cell-cycle arrest and trigger premature senescence of HepG2 cells; suggests that the growth-arrest and senescence induction capability on cancer cells suggest anticancer potential of Ganoderiol F. It could be developed further as both anti-HIV and antimalaria.In Compared to plasmepsin I, ganoderiol-F is higher towards HIV-1 protease.
- Molecular Weight: 454.7
- Molecular Formula: C30H46O3
Purity: >98%
- Boiling Point: 598.3±50.0 °C(Predicted)
- Melting Point: 116-120 °C
- Appearance: Powder
- Application: anti-inflammatory; anti-HIV;
Synonyms:
26,27-Dihydroxylanosta-7,9(11),24-trien-3-one
More details are to be found on supplier website
