Description:
Omeprazole EP Impurity B is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen.
- Molecular Weight: 315.39
- Molecular Formula: C16H17N3O2S
Purity: >95%
Canonical SMILES:
CC1=CC(=C(N=C1)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC)C
InChI:
InChI=1S/C16H17N3O2S/c1-10-6-11(2)15(17-8-10)9-22(20)16-18-13-5-4-12(21-3)7-14(13)19-16/h4-8H,9H2,1-3H3,(H,18,19)
InChIKey: ZMXZYNHJPJEPAE-UHFFFAOYSA-N
- Melting Point: >142°C (dec.)
- Solubility: Soluble in EtOH (~5 mg/ml at 25°C), DMSO & DMF (~30 mg/ml at 25°C), and DMSO: PBS (1: 1 pH 7.2) (~0.5 mg/ml at 25°C)
- Appearance: Off-white to Beige to Yellow Powder
- Storage: Store at -20°C
Synonyms:
Esomeprazole EP Impurity B; 4-desmethoxy Omeprazole; H 180/29; 2-[(RS)-[(3,5-Dimethylpyridin-2-yl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole
More details are to be found on supplier website
