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BGC > CAS Search > 929016-96-6
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Suppliers for CAS

929016-96-6



 

Properties

CAS   929016-96-6 
Formula   C20H30N4O2 

Structure

6 Registered suppliers


Leap Chem Co., Ltd P.R.China
Aea.ltd P.R.China
Molecular Formula: C20H30N4O2
Molecular Weight: 358.4778
Molecular Formula: C20H30N4O2
Molecular Weight: 358.4778
BOC Sciences USA
AK Scientific, Inc. USA
Description :
Pracinostat (SB939) is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. Pracinostat inhibits HDACs, which may result in the accumulation of highly acetylated histones, followed by the induction of chromatin remodeling; the selective transcription of tumor suppressor genes; the tumor suppressor protein-mediated inhibition of tumor cell division; and, finally, the induction of tumor cell apoptosis. This agent may possess improved metabolic, pharmacokinetic and pharmacological properties compared to other HDAC inhibitors.
  • Molecular Weight :358.486
  • Purity :> 98%
Molecular Formula :
C20H30N4O2
Canonical SMILES :
CCCCC1=NC2=C(N1CCN(CC)CC)C=CC(=C2)C=CC(=O)NO
InChI :
InChI=1S/C20H30N4O2/c1-4-7-8-19-21-17-15-16(10-12-20(25)22-26)9-11-18(17)24(19)14-13-23(5-2)6-3/h9-12,15,26H,4-8,13-14H2,1-3H3,(H,22,25)/b12-10+
InChIKey :
JHDKZFFAIZKUCU-ZRDIBKRKSA-N
Appearance :
white solid powder
Synonyms :
SB939; SB 939; SB-939; SC-939; SC 939; SC939; Pracinostat.
More details are to be found here
Chemos GmbH & Co. KG Germany
Description :
Pracinostat (SB939) is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. Pracinostat inhibits HDACs, which may result in the accumulation of highly acetylated histones, followed by the induction of chromatin remodeling; the selective transcription of tumor suppressor genes; the tumor suppressor protein-mediated inhibition of tumor cell division; and, finally, the induction of tumor cell apoptosis. This agent may possess improved metabolic, pharmacokinetic and pharmacological properties compared to other HDAC inhibitors.
  • Molecular Weight :358.486
  • Purity :> 98%
Molecular Formula :
C20H30N4O2
Canonical SMILES :
CCCCC1=NC2=C(N1CCN(CC)CC)C=CC(=C2)C=CC(=O)NO
InChI :
InChI=1S/C20H30N4O2/c1-4-7-8-19-21-17-15-16(10-12-20(25)22-26)9-11-18(17)24(19)14-13-23(5-2)6-3/h9-12,15,26H,4-8,13-14H2,1-3H3,(H,22,25)/b12-10+
InChIKey :
JHDKZFFAIZKUCU-ZRDIBKRKSA-N
Appearance :
white solid powder
Synonyms :
SB939; SB 939; SB-939; SC-939; SC 939; SC939; Pracinostat.
More details are to be found here
Santa Cruz Biotechnology, Inc. USA
Description :
Pracinostat (SB939) is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. Pracinostat inhibits HDACs, which may result in the accumulation of highly acetylated histones, followed by the induction of chromatin remodeling; the selective transcription of tumor suppressor genes; the tumor suppressor protein-mediated inhibition of tumor cell division; and, finally, the induction of tumor cell apoptosis. This agent may possess improved metabolic, pharmacokinetic and pharmacological properties compared to other HDAC inhibitors.
  • Molecular Weight :358.486
  • Purity :> 98%
Molecular Formula :
C20H30N4O2
Canonical SMILES :
CCCCC1=NC2=C(N1CCN(CC)CC)C=CC(=C2)C=CC(=O)NO
InChI :
InChI=1S/C20H30N4O2/c1-4-7-8-19-21-17-15-16(10-12-20(25)22-26)9-11-18(17)24(19)14-13-23(5-2)6-3/h9-12,15,26H,4-8,13-14H2,1-3H3,(H,22,25)/b12-10+
InChIKey :
JHDKZFFAIZKUCU-ZRDIBKRKSA-N
Appearance :
white solid powder
Synonyms :
SB939; SB 939; SB-939; SC-939; SC 939; SC939; Pracinostat.
More details are to be found here

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