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BGC > CAS Search > 796967-16-3
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Suppliers for CAS

796967-16-3



 

Properties

CAS   796967-16-3 
Formula   C21H18FN5

Structure

9 Registered suppliers


Capot Chemical Co., Ltd. P.R.China
Leap Chem Co., Ltd P.R.China
Aea.ltd P.R.China
Molecular Formula: C21H18FN5O
Molecular Weight: 375.405
Molecular Formula: C21H18FN5O
Molecular Weight: 375.405
Hangzhou Zhongqi Chem Co., Ltd P.R.China
Molecular Formula: C21H18FN5O
Molecular Weight: 375.405
Hangzhou Lingrui Chemical Co., Ltd. P.R.China
Molecular Formula: C21H18FN5O
Molecular Weight: 375.405
Skyrun Industrial Co., Ltd. P.R.China
Molecular Formula: C21H18FN5O
Molecular Weight: 375.405
BOC Sciences USA
CM Fine Chemicals Switzerland
Description :
Description of Linifanib: Linifanib is an orally bioavailable, small-molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Linifanib inhibits members of the vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) receptor families; it exhibits much less activity against unrelated RTKs, soluble tyrosine kinases, or serine/threonine kinases. This agent does not have a general antiproliferative effect due to its high dose requirement. However, linifanib may exhibit potent antiproliferative and apoptotic effects on tumor cells whose proliferation is dependent on mutant kinases, such as fms-related tyrosine kinase receptor-3 (FLT3).
  • Molecular Weight :375.407
Molecular Formula :
C21H18FN5O
Canonical SMILES :
CC1=CC(=C(C=C1)F)NC(=O)NC2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N
InChI :
InChI=1S/C21H18FN5O/c1-12-5-10-16(22)18(11-12)25-21(28)24-14-8-6-13(7-9-14)15-3-2-4-17-19(15)20(23)27-26-17/h2-11H,1H3,(H3,23,26,27)(H2,24,25,28)
InChIKey :
MPVGZUGXCQEXTM-UHFFFAOYSA-N
Synonyms :
ABT869; ABT 869; ABT-869; Linifanib
More details are to be found here
Santa Cruz Biotechnology, Inc. USA
Description :
Description of Linifanib: Linifanib is an orally bioavailable, small-molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Linifanib inhibits members of the vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) receptor families; it exhibits much less activity against unrelated RTKs, soluble tyrosine kinases, or serine/threonine kinases. This agent does not have a general antiproliferative effect due to its high dose requirement. However, linifanib may exhibit potent antiproliferative and apoptotic effects on tumor cells whose proliferation is dependent on mutant kinases, such as fms-related tyrosine kinase receptor-3 (FLT3).
  • Molecular Weight :375.407
Molecular Formula :
C21H18FN5O
Canonical SMILES :
CC1=CC(=C(C=C1)F)NC(=O)NC2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N
InChI :
InChI=1S/C21H18FN5O/c1-12-5-10-16(22)18(11-12)25-21(28)24-14-8-6-13(7-9-14)15-3-2-4-17-19(15)20(23)27-26-17/h2-11H,1H3,(H3,23,26,27)(H2,24,25,28)
InChIKey :
MPVGZUGXCQEXTM-UHFFFAOYSA-N
Synonyms :
ABT869; ABT 869; ABT-869; Linifanib
More details are to be found here

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