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Suppliers for
Nestorone
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Properties | CAS |
7759-35-5 | Formula |
C23H30O4 |
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7 Registered suppliers
Molecular Formula: C23H30O4 Molecular Weight: 370.48 WGKGermany: 3
More details are to be found here
Molecular Formula: C23H30O4 Molecular Weight: 370.48 WGKGermany: 3
More details are to be found here
Molecular Formula: C23H30O4 Molecular Weight: 370.48 WGKGermany: 3
More details are to be found here
Description : Nestorone is a steroidal progestin of the 19-norprogesterone group which is used as a hormonal contraceptive in several South American countries. It is a potent progesterone receptor agonist with no androgenic, estrogenic, or glucocorticoid-like activities. It has been used as a female contraceptive and may be useful as a male contraceptive too recently. It does not bind to the estrogen receptor either, but it has some affinity for the glucocorticoid receptor. It appears to act as an agonist, but it does not appear to produce any glucocorticoid side effects unless used at high doses. It has been shown to have neurogenic and neuroprotective activity. It holds back proinflammatory mediators and neuropathology in the wobbler mouse model of motoneuron degeneration. It protected against hippocampus abnormalities and improved functional outcomes of EAE mice, which suggests its potential value. It lacks affinity for the androgen receptor, thus does not produce any androgenic or anabolic effects. - Molecular Weight :370.48
- Boiling Point :499.3±45.0 °C | Condition: Press: 760 Torr
- Purity :95%
Molecular Formula : C23H30O4 Canonical SMILES : CC(=O)C1(C(=C)CC2C1(CCC3C2CCC4=CC(=O)CCC34)C)OC(=O)C InChI : InChI=1S/C23H30O4/c1-13-11-21-20-7-5-16-12-17(26)6-8-18(16)19(20)9-10-22(21,4)23(13,14(2)24)27-15(3)25/h12,18-21H,1,5-11H2,2-4H3/t18-,19+,20+,21-,22-,23-/m0/s1 InChIKey : CKFBRGLGTWAVLG-GOMYTPFNSA-N Solubility : 10 mM in DMSO Appearance : White to beige powder Application : Nestorone is used as a hormonal contraceptive in several South American countries. It has been used as a female contraceptive and may be useful as a male contraceptive too recently. It lacks affinity for the androgen receptor, thus does not produce any androgenic or anabolic effects. Storage : -20°C Freezer Synonyms : ST-1435; ST1435; ST1435; Elcometrine; Nestorone; segesterone acetate; 17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate; Elcometrine; 16-Methylene-17-hydroxy-19-norpregn-4-ene-3,20-dione acetate; Segesterone acetate; [(8R,9S,10R,13S,14S,17R)-17-acetyl-13-methyl-16-methylidene-3-oxo-2,6,7,8,9,10,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
More details are to be found here
Description : Nestorone is a steroidal progestin of the 19-norprogesterone group which is used as a hormonal contraceptive in several South American countries. It is a potent progesterone receptor agonist with no androgenic, estrogenic, or glucocorticoid-like activities. It has been used as a female contraceptive and may be useful as a male contraceptive too recently. It does not bind to the estrogen receptor either, but it has some affinity for the glucocorticoid receptor. It appears to act as an agonist, but it does not appear to produce any glucocorticoid side effects unless used at high doses. It has been shown to have neurogenic and neuroprotective activity. It holds back proinflammatory mediators and neuropathology in the wobbler mouse model of motoneuron degeneration. It protected against hippocampus abnormalities and improved functional outcomes of EAE mice, which suggests its potential value. It lacks affinity for the androgen receptor, thus does not produce any androgenic or anabolic effects. - Molecular Weight :370.48
- Boiling Point :499.3±45.0 °C | Condition: Press: 760 Torr
- Purity :95%
Molecular Formula : C23H30O4 Canonical SMILES : CC(=O)C1(C(=C)CC2C1(CCC3C2CCC4=CC(=O)CCC34)C)OC(=O)C InChI : InChI=1S/C23H30O4/c1-13-11-21-20-7-5-16-12-17(26)6-8-18(16)19(20)9-10-22(21,4)23(13,14(2)24)27-15(3)25/h12,18-21H,1,5-11H2,2-4H3/t18-,19+,20+,21-,22-,23-/m0/s1 InChIKey : CKFBRGLGTWAVLG-GOMYTPFNSA-N Solubility : 10 mM in DMSO Appearance : White to beige powder Application : Nestorone is used as a hormonal contraceptive in several South American countries. It has been used as a female contraceptive and may be useful as a male contraceptive too recently. It lacks affinity for the androgen receptor, thus does not produce any androgenic or anabolic effects. Storage : -20°C Freezer Synonyms : ST-1435; ST1435; ST1435; Elcometrine; Nestorone; segesterone acetate; 17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate; Elcometrine; 16-Methylene-17-hydroxy-19-norpregn-4-ene-3,20-dione acetate; Segesterone acetate; [(8R,9S,10R,13S,14S,17R)-17-acetyl-13-methyl-16-methylidene-3-oxo-2,6,7,8,9,10,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
More details are to be found here
Description : Nestorone is a steroidal progestin of the 19-norprogesterone group which is used as a hormonal contraceptive in several South American countries. It is a potent progesterone receptor agonist with no androgenic, estrogenic, or glucocorticoid-like activities. It has been used as a female contraceptive and may be useful as a male contraceptive too recently. It does not bind to the estrogen receptor either, but it has some affinity for the glucocorticoid receptor. It appears to act as an agonist, but it does not appear to produce any glucocorticoid side effects unless used at high doses. It has been shown to have neurogenic and neuroprotective activity. It holds back proinflammatory mediators and neuropathology in the wobbler mouse model of motoneuron degeneration. It protected against hippocampus abnormalities and improved functional outcomes of EAE mice, which suggests its potential value. It lacks affinity for the androgen receptor, thus does not produce any androgenic or anabolic effects. - Molecular Weight :370.48
- Boiling Point :499.3±45.0 °C | Condition: Press: 760 Torr
- Purity :95%
Molecular Formula : C23H30O4 Canonical SMILES : CC(=O)C1(C(=C)CC2C1(CCC3C2CCC4=CC(=O)CCC34)C)OC(=O)C InChI : InChI=1S/C23H30O4/c1-13-11-21-20-7-5-16-12-17(26)6-8-18(16)19(20)9-10-22(21,4)23(13,14(2)24)27-15(3)25/h12,18-21H,1,5-11H2,2-4H3/t18-,19+,20+,21-,22-,23-/m0/s1 InChIKey : CKFBRGLGTWAVLG-GOMYTPFNSA-N Solubility : 10 mM in DMSO Appearance : White to beige powder Application : Nestorone is used as a hormonal contraceptive in several South American countries. It has been used as a female contraceptive and may be useful as a male contraceptive too recently. It lacks affinity for the androgen receptor, thus does not produce any androgenic or anabolic effects. Storage : -20°C Freezer Synonyms : ST-1435; ST1435; ST1435; Elcometrine; Nestorone; segesterone acetate; 17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate; Elcometrine; 16-Methylene-17-hydroxy-19-norpregn-4-ene-3,20-dione acetate; Segesterone acetate; [(8R,9S,10R,13S,14S,17R)-17-acetyl-13-methyl-16-methylidene-3-oxo-2,6,7,8,9,10,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
More details are to be found here
Description : Nestorone is a steroidal progestin of the 19-norprogesterone group which is used as a hormonal contraceptive in several South American countries. It is a potent progesterone receptor agonist with no androgenic, estrogenic, or glucocorticoid-like activities. It has been used as a female contraceptive and may be useful as a male contraceptive too recently. It does not bind to the estrogen receptor either, but it has some affinity for the glucocorticoid receptor. It appears to act as an agonist, but it does not appear to produce any glucocorticoid side effects unless used at high doses. It has been shown to have neurogenic and neuroprotective activity. It holds back proinflammatory mediators and neuropathology in the wobbler mouse model of motoneuron degeneration. It protected against hippocampus abnormalities and improved functional outcomes of EAE mice, which suggests its potential value. It lacks affinity for the androgen receptor, thus does not produce any androgenic or anabolic effects. - Molecular Weight :370.48
- Boiling Point :499.3±45.0 °C | Condition: Press: 760 Torr
- Purity :95%
Molecular Formula : C23H30O4 Canonical SMILES : CC(=O)C1(C(=C)CC2C1(CCC3C2CCC4=CC(=O)CCC34)C)OC(=O)C InChI : InChI=1S/C23H30O4/c1-13-11-21-20-7-5-16-12-17(26)6-8-18(16)19(20)9-10-22(21,4)23(13,14(2)24)27-15(3)25/h12,18-21H,1,5-11H2,2-4H3/t18-,19+,20+,21-,22-,23-/m0/s1 InChIKey : CKFBRGLGTWAVLG-GOMYTPFNSA-N Solubility : 10 mM in DMSO Appearance : White to beige powder Application : Nestorone is used as a hormonal contraceptive in several South American countries. It has been used as a female contraceptive and may be useful as a male contraceptive too recently. It lacks affinity for the androgen receptor, thus does not produce any androgenic or anabolic effects. Storage : -20°C Freezer Synonyms : ST-1435; ST1435; ST1435; Elcometrine; Nestorone; segesterone acetate; 17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate; Elcometrine; 16-Methylene-17-hydroxy-19-norpregn-4-ene-3,20-dione acetate; Segesterone acetate; [(8R,9S,10R,13S,14S,17R)-17-acetyl-13-methyl-16-methylidene-3-oxo-2,6,7,8,9,10,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
More details are to be found here
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Nestorone
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Last update 2024-05-28
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