BGC > CAS Search > 68392-35-8

Molecular Formula: C26H29NO2
Molecular Weight: 387.51
Hazard Symbols: Xn
UN Number: UN1170 - class 3 - PG 2 - Ethanol, solution
WGKGermany: 3

Molecular Formula: C26H29NO2
Molecular Weight: 387.51
Hazard Symbols: Xn
UN Number: UN1170 - class 3 - PG 2 - Ethanol, solution
WGKGermany: 3

Description :
Afimoxifene (4-hydroxytamoxifen) is a selective estrogen receptor modulator which is the active metabolite of tamoxifen. Afimoxifene is a transdermal gel formulation and is being developed by Ascend Therapeutics, Inc. under the trademark TamoGel. Afimoxifene has completed a phase II clinical trial for the treatment of cyclical mastalgia.

• Molecular Weight :387.51
• Boiling Point :514.4±50.0°C (Predicted)
• Melting Point :135-144°C
• Purity :≥95%

Molecular Formula :
C26H29NO2
Canonical SMILES :
CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3
InChI :
InChI=1S/C26H29NO2/c1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3
InChIKey :
TXUZVZSFRXZGTL-UHFFFAOYSA-N
Solubility :
Soluble in Dichloromethane (Slightly), Methanol (Slightly)
Appearance :
White to Off-white Solid
Application :
Estrogen Antagonists
Storage : Store at 2-8°C
Synonyms :
(E/Z)-4-Hydroxytamoxifen; 4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol; TamoGel; Phenol, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-

More details are to be found here

Description :
Afimoxifene (4-hydroxytamoxifen) is a selective estrogen receptor modulator which is the active metabolite of tamoxifen. Afimoxifene is a transdermal gel formulation and is being developed by Ascend Therapeutics, Inc. under the trademark TamoGel. Afimoxifene has completed a phase II clinical trial for the treatment of cyclical mastalgia.

• Molecular Weight :387.51
• Boiling Point :514.4±50.0°C (Predicted)
• Melting Point :135-144°C
• Purity :≥95%

Molecular Formula :
C26H29NO2
Canonical SMILES :
CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3
InChI :
InChI=1S/C26H29NO2/c1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3
InChIKey :
TXUZVZSFRXZGTL-UHFFFAOYSA-N
Solubility :
Soluble in Dichloromethane (Slightly), Methanol (Slightly)
Appearance :
White to Off-white Solid
Application :
Estrogen Antagonists
Storage : Store at 2-8°C
Synonyms :
(E/Z)-4-Hydroxytamoxifen; 4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol; TamoGel; Phenol, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-

More details are to be found here

Description :
Afimoxifene (4-hydroxytamoxifen) is a selective estrogen receptor modulator which is the active metabolite of tamoxifen. Afimoxifene is a transdermal gel formulation and is being developed by Ascend Therapeutics, Inc. under the trademark TamoGel. Afimoxifene has completed a phase II clinical trial for the treatment of cyclical mastalgia.

• Molecular Weight :387.51
• Boiling Point :514.4±50.0°C (Predicted)
• Melting Point :135-144°C
• Purity :≥95%

Molecular Formula :
C26H29NO2
Canonical SMILES :
CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3
InChI :
InChI=1S/C26H29NO2/c1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3
InChIKey :
TXUZVZSFRXZGTL-UHFFFAOYSA-N
Solubility :
Soluble in Dichloromethane (Slightly), Methanol (Slightly)
Appearance :
White to Off-white Solid
Application :
Estrogen Antagonists
Storage : Store at 2-8°C
Synonyms :
(E/Z)-4-Hydroxytamoxifen; 4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol; TamoGel; Phenol, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-

More details are to be found here