BGC > CAS Search > 2341840-99-9

Description :
Thalidomide 4'-ether-alkylC2-amine hydrochloride is a synthetic E3 ligand-linker conjugate containing a cereblon ligand based on Thalidomide and a short C2 alkyl linker with terminal amine for covalent binding, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand.

• Molecular Weight :353.76
• Purity :≥95% by HPLC

Molecular Formula :
C₁₅H₁₆ClN₃O₅
Canonical SMILES :
NCCOC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O.Cl
InChI :
1S/C15H15N3O5.ClH/c16-6-7-23-10-3-1-2-8-12(10)15(22)18(14(8)21)9-4-5-11(19)17-13(9)20;/h1-3,9H,4-7,16H2,(H,17,19,20);1H
InChIKey :
AZQNUQDFOMUSBB-UHFFFAOYSA-N
Storage : Store at -20°C
Synonyms :
Thalidomide - linker 6

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