BGC > CAS Search > 1204669-58-8

Molecular Formula: C11H13BrFN7O4S
Molecular Weight: 438.2328232

Molecular Formula: C11H13BrFN7O4S
Molecular Weight: 438.2328232

Description :
Epacadostat, also known as INCB024360 or INCB24360, is a potent and selective IDO1 inhibitor with IC50 of 71.8 nM±17.5 nM, with potential immunomodulating and antineoplastic activities. It has been shown to promote T and natural killer-cell growth, to increase IFN-γ production, and to reduce conversion to regulatory T (Treg)-like cells in a coculture system of human allogeneic lymphocytes with either dendritic cells or tumor cells.

• Molecular Weight :438.23
• Boiling Point :700.9±70.0°C at 760 mmHg
• Melting Point :159-161°C
• Purity :≥95%

Molecular Formula :
C11H13BrFN7O4S
Canonical SMILES :
O=S(=O)(N)NCCNC1=NON=C1C(=NO)NC2=CC=C(F)C(Br)=C2
InChI :
InChI=1S/C11H13BrFN7O4S/c12-7-5-6(1-2-8(7)13)17-11(18-21)9-10(20-24-19-9)15-3-4-16-25(14,22)23/h1-2,5,16,21H,3-4H2,(H,15,20)(H,17,18)(H2,14,22,23)
InChIKey :
FBKMWOJEPMPVTQ-UHFFFAOYSA-N
Solubility :
Soluble in DMSO (Slightly), Methanol (Slightly)
Appearance :
White to off-white solid powder
Storage : Store at -20°C
Synonyms :
IDO inhibitor 1; 1,2,5-Oxadiazole-3-carboximidamide, 4-[[2-[(aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-, [C(Z)]-; [C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide; ICBN 24360; ICBN-24360; ICBN24360; INCB 024360; INCB024360; INCB-024360

More details are to be found here

Purity : 98+%
Smile code : O=S(NCCNC1=NON=C1/C(NC2=CC=C(F)C(Br)=C2)=N/O)(N)=O
MDL Number : MFCD26142934
MolFormula : C11H13BrFN7O4S
MolWeight : 438.2328
Available in stock : 21.989

More details are to be found here

Smile code:
O=S(NCCNC1=NON=C1/C(NC2=CC=C(F)C(Br)=C2)=N/O)(N)=O
MDL Number:
MFCD26142934
Purity :
98+%
Available in stock:
22.777 g

More details are to be found here

Smile code:
O=S(NCCNC1=NON=C1/C(NC2=CC=C(F)C(Br)=C2)=N/O)(N)=O
MDL Number:
MFCD26142934
Purity :
98+%
Available in stock:
22.777 g

More details are to be found here