BGC > CAS Search > 1110766-97-6

Molecular Formula: C29H32Cl2N2O5S
Molecular Weight: 591.54578

Molecular Formula: C29H32Cl2N2O5S
Molecular Weight: 591.54578

Description :
Lusutrombopag is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist. It acts selectively on the human TPO receptor and activates signal transduction pathways and thereby increases platelet levels. It was developed by Shionogi for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery. It has been listed.

• Molecular Weight :591.54
• Purity :> 98%

Molecular Formula :
C29H32Cl2N2O5S
Canonical SMILES :
CCCCCCOC(C)C1=CC=CC(=C1OC)C2=CSC(=N2)NC(=O)C3=CC(=C(C(=C3)Cl)C=C(C)C(=O)O)Cl
InChI :
InChI=1S/C29H32Cl2N2O5S/c1-5-6-7-8-12-38-18(3)20-10-9-11-21(26(20)37-4)25-16-39-29(32-25)33-27(34)19-14-23(30)22(24(31)15-19)13-17(2)28(35)36/h9-11,13-16,18H,5-8,12H2,1-4H3,(H,35,36)(H,32,33,34)/b17-13+/t18-/m0/s1
InChIKey :
NOZIJMHMKORZBA-KJCUYJGMSA-N
Solubility :
10 mM in DMSO
Appearance :
Solid powder
Application :
Lusutrombopag was used for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery.
Storage : -20°C Freezer
Synonyms :
S-888711; S 888711; S888711; (E)-3-[2,6-dichloro-4-[[4-[3-[(1S)-1-hexoxyethyl]-2-methoxyphenyl]-1,3-thiazol-2-yl]carbamoyl]phenyl]-2-methylprop-2-enoic acid

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