BGC > CAS Search > 87760-53-0

Molecular Formula: C21H29N5O2
Molecular Weight: 383.49
Hazard Symbols: Xi
WGKGermany: 3

Molecular Formula: C21H30ClN5O2
Molecular Weight: 419.9482

Molecular Formula: C21H30ClN5O2
Molecular Weight: 419.9482

Description :
Tandospirone is a potent and selective 5-HT1A receptor partial agonist with Ki of 27 nM. It significantly reduces haloperidol-induced bradykinesia in a dose dependent manner. It also decreased the number of premature responses in a dose-dependent manner. It is used as an antidepressant.

• Molecular Weight :383.49
• Boiling Point :613.9±65.0 °C (Predicted)
• Melting Point :110-113 °C (dec.)
• Purity :> 98%

Molecular Formula :
C21H29N5O2
Canonical SMILES :
C1CC2CC1C3C2C(=O)N(C3=O)CCCCN4CCN(CC4)C5=NC=CC=N5
InChI :
InChI=1S/C21H29N5O2/c27-19-17-15-4-5-16(14-15)18(17)20(28)26(19)9-2-1-8-24-10-12-25(13-11-24)21-22-6-3-7-23-21/h3,6-7,15-18H,1-2,4-5,8-14H2/t15-,16+,17+,18-
InChIKey :
CEIJFEGBUDEYSX-FZDBZEDMSA-N
Solubility :
Slightly soluble in Chloroform, Methanol; Soluble in DMSO (38 mg/mL)
Appearance :
white Solid
Application :
Tandospironeis is used as an antidepressant.
Storage : 2-8 °C
Synonyms :
(3aR,4S,7R,7aS)-2-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione; Metanopirone; Sediel; SM-3997; SM 3997; SM3997; 4,7-Methano-1H-isoindole-1,3(2H)-dione, hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-, (3aa,4b,7b,7aa)-; (3αα,4β,7β,7αα)-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione; (3aR,4S,7R,7aS)-rel-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dionehydrochloride

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