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Suppliers for
AZD0364
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Properties | CAS |
2097416-76-5 |
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3 Registered suppliers
Description : AZD-0364 is a potent and selective ERK2 inhibitor, which has an IC50 value of 0.6 nM. AZD-0364 is measured in the A375 phospho-p90RSK assays with IC50s of 5.7 nM. AZD-0364 can inhibit the growth of a panel of cancer cell lines. The combination of Selumetinib and AZD-0364 ethanesulfonic acid results in a reduction in tumor growth. - Molecular Weight :494.50
- Boiling Point :716.0±70.0 °C(Predicted)
- Purity :≥98%
Molecular Formula : C24H24F2N8O2 Canonical SMILES : O=C1C2=NC(C3=NC(NC4=CC=NN4C)=NC=C3C)=CN2C[C@H](COC)N1CC5=CC=C(F)C(F)=C5 InChI : InChI=1S/C24H24F2N8O2/c1-14-9-27-24(30-20-6-7-28-32(20)2)31-21(14)19-12-33-11-16(13-36-3)34(23(35)22(33)29-19)10-15-4-5-17(25)18(26)8-15/h4-9,12,16H,10-11,13H2,1-3H3,(H,27,30,31)/t16-/m1/s1 InChIKey : HVIGNZUDBVLTLU-MRXNPFEDSA-N Solubility : Soluble to 202.22 mM in DMSO. Appearance : Solid Powder Synonyms : AZD-0364; AZD 0364; tizaterkib
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AZD0364
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Last update 2024-05-13
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