www.BuyersGuideChem.com - the directory of chemicals and chemical suppliers. The search engine opens a large data base and offers new supply sources
Welcome About BGC Terms of Use MSDS Banner Adverts Statistics Impressum Sitemap
BGC > Product Search > 5-[2,4-Dihydroxy-5-(1-methylethyl)phenyl]-N-ethyl-4-[4-(4-morpholinylmethyl)phenyl]-3-isoxazolecarboxamide | 747412-49-3
english deutsch español

Suppliers for CAS

747412-49-3


Properties

CAS   747412-49-3 
Formula   C26H31N3O5 

Structure

6 Registered suppliers


Capot Chemical Co., Ltd. P.R.China
Leap Chem Co., Ltd P.R.China
Aea.ltd P.R.China
Molecular Formula: C26H31N3O5
Molecular Weight: 465.547
Molecular Formula: C26H31N3O5
Molecular Weight: 465.547
BOC Sciences USA
Chemos GmbH & Co. KG Germany
Description :
Luminespib, also known as AUY-922 (or NVP-AUY922), is a derivative of 4,5-diarylisoxazole and a third-generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY922 has been shown to bind with high affinity to and inhibit Hsp90, resulting in the proteasomal degradation of oncogenic client proteins.
  • Molecular Weight :465.54
  • Boiling Point :640.1±55.0 °C at 760 mmHg
  • Purity :> 98%
Molecular Formula :
C26H31N3O5
Canonical SMILES :
CCNC(=O)C1=C(C(=C2C=C(C(=CC2=O)O)C(C)C)ON1)C3=CC=C(C=C3)CN4CCOCC4
InChI :
InChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33-12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8,13-14,16,28,30H,4,9-12,15H2,1-3H3,(H,27,32)/b25-20-
InChIKey :
SWDZPNJZKUGIIH-QQTULTPQSA-N
Solubility :
DMSO:37 mg/mL
Appearance :
Solid powder
Storage : 3 years -20oC powder, 6 months-80oC in solvent.
Synonyms :
Luminespib; AUY-922; AUY922; AUY 922; NVP-AUY-922; NVP-AUY922; VER-52296; VER52296; VER 52296;
More details are to be found here
Santa Cruz Biotechnology, Inc. USA
Description :
Luminespib, also known as AUY-922 (or NVP-AUY922), is a derivative of 4,5-diarylisoxazole and a third-generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY922 has been shown to bind with high affinity to and inhibit Hsp90, resulting in the proteasomal degradation of oncogenic client proteins.
  • Molecular Weight :465.54
  • Boiling Point :640.1±55.0 °C at 760 mmHg
  • Purity :> 98%
Molecular Formula :
C26H31N3O5
Canonical SMILES :
CCNC(=O)C1=C(C(=C2C=C(C(=CC2=O)O)C(C)C)ON1)C3=CC=C(C=C3)CN4CCOCC4
InChI :
InChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33-12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8,13-14,16,28,30H,4,9-12,15H2,1-3H3,(H,27,32)/b25-20-
InChIKey :
SWDZPNJZKUGIIH-QQTULTPQSA-N
Solubility :
DMSO:37 mg/mL
Appearance :
Solid powder
Storage : 3 years -20oC powder, 6 months-80oC in solvent.
Synonyms :
Luminespib; AUY-922; AUY922; AUY 922; NVP-AUY-922; NVP-AUY922; VER-52296; VER52296; VER 52296;
More details are to be found here


© Copyright 1996 to 2024 by Netvertise GmbH. All rights reserved