BGC > Buscar Producto > Fostriecin sodium salt | 87860-39-7

Molecular Formula: C19H26NaO9P
Molecular Weight: 452.37
WGKGermany: 3

Description:
Fostriecin sodium salt is a protein phosphatase types 2A (PP2A) and 4 (PP4) inhibitor (IC50 = 1.5 nM and 3 nM, respectively). It also has an inhibitory effect on topoisomerase II (IC50 = 40 μM) and protein phosphatase type 1 (PP1) (IC50 = 131 μM). Fostriecin is found in Streptomyces pulveraceous.

• Molecular Weight:452.37
• Purity:≥98% by HPLC

Molecular Formula:
C19H26O9PNa
Canonical SMILES:
[Na].O=C1OC(C=CC(O)(C)C(OP(=O)(O)O)CC(O)C=CC=CC=CCO)CC=C1
InChI:
InChI=1S/C19H27O9P.Na/c1-19(23,12-11-16-9-7-10-18(22)27-16)17(28-29(24,25)26)14-15(21)8-5-3-2-4-6-13-20;/h2-8,10-12,15-17,20-21,23H,9,1314H2,1H3,(H2,24,25,26);/b3-2-,6-4+,8-5-,12-11+;/t15-,16+,17+,19+;/m0./s1
InChIKey:
JUSDOSJWBHHCBI-IAVQPKKASA-N
Solubility:
Water > 300 (mg/mL)
Application:
Enzyme Inhibitors
Synonyms:
Fostriecin Sodium; Antibiotic CI 920 sodium salt; (6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one sodium salt