BGC > Buscar Producto > Artesunate | 88495-63-0

Appearance	White crystalline powder, odorless
Solubility	Free soluble in ethanol, acetone or chloroform,very slightly soluble in water
Specific optical rotation	+4.5º-+6.5º
Identification
TLC	The principal spot in the chromatogram obtained with the test solution is similar in position, colour to the principal spot in the chromatogram obtained with the reference solution
HPLC	The retention time of main peak of test and standard are concordant
IR	Infrared absorption spectrum of test and standard (or infrared reference spectra No.221) are concordant
Acidity	3.5-4.5
Appearance of solution	Solution S is clear and not more intensely colored than reference solution
Chlorides	Not more pronounced(0.02%)
Related substances(HPLC)
Dihydroartemisinin	≤ 1.0%
Artemisinin	≤ 0.5%
Impurity I	≤ 0.2%
Any other impurity	≤ 0.2%
Total impurites	≤ 2.0%
Water	≤ 0.5%
Residual on ignition	≤ 0.1%
Heavy metal	≤ 20PPM
Bacterial endotoxin	≤ 1.25EU
Assy(HPLC)	98.0-102.0%

Molecular Formula: C19H28O8
Molecular Weight: 384,42

Description:
Artesunate is a derivative of the natural product artemisinin which effectively kills the malarial parasites P. falciparum and P. vivax. It also kills trematodes of the species Schistosoma, providing protection against schistosomiasis.

• Molecular Weight:384.42
• Boiling Point:507.1±50.0 °C at 760 mmHg
• Melting Point:131-135 °C
• Purity:>99%

Molecular Formula:
C19H28O8
Canonical SMILES:
CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC(=O)CCC(=O)O)C
InChI:
InChI=1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16+,17-,18?,19-/m1/s1
InChIKey:
FIHJKUPKCHIPAT-JQXDXKTESA-N
Solubility:
Soluble in DMSO (25 mg/ml), and ethanol (25 mg/ml)
Appearance:
White Powder
Storage: Store at +4 °C, in dark place.
Synonyms:
Succinyl dihydroartemisinin; Dihydroartemisinine-12-alpha-succinate; Artesunate (superseded RN); Artesunate; Armax 200; SM-804; WR-256283; HSDB-7458; SM804; WR256283; HSDB7458; SM 804; WR 256283; HSDB 7458