BGC > Buscar Producto > Afatinib | 439081-18-2

Molecular Formula: C24H25ClFN5O3
Molecular Weight: 485.944
HS Code: 29349990

Molecular Formula: C24H25ClFN5O3
Molecular Weight: 485.94

Appearance	white powder
Purity	99% min
It is used to treat cancers and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct and gallbladder.

Description:
N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide is an impurity of Afatinib, which is a tyrosine kinase inhibitor used to treat non-small cell lung carcinoma (NSCLC).

• Molecular Weight:485.94
• Boiling Point:676.9±55.0°C at 760 mmHg
• Purity:98%

Molecular Formula:
C24H25ClFN5O3
Canonical SMILES:
CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4
InChI:
InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/t16-/m0/s1
InChIKey:
ULXXDDBFHOBEHA-INIZCTEOSA-N
Solubility:
Soluble in DMSO (Slightly), Methanol (Slightly)
Appearance:
White to Pale Yellow Solid
Application:
Antineoplastic Agents
Storage: Store at 2-8°C
Synonyms:
2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-; (S)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide