BGC > Buscar Producto > 6-[(1-Acetylpiperidin-4-yl)amino]-N-[(2S)-2-hydroxy-3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]pyrimidine-4-carboxamide | 1616392-22-3

Molecular Formula: C24H32N6O3
Molecular Weight: 452.54928

Description:
GSK3326595, also called as EPZ015938, is an orally available and specific inhibitor of protein arginine methyltransferase 5 (PRMT5) that potently inhibits tumor growth in vitro and in vivo in animal models and has entered clinical trials for the treatment of solid tumors and non-Hodgkin's lymphoma.

• Molecular Weight:452.55
• Boiling Point:760.3±60.0 ℃ at 760 Torr

Molecular Formula:
C24H32N6O3
Canonical SMILES:
CC(=O)N1CCC(CC1)NC2=NC=NC(=C2)C(=O)NCC(CN3CCC4=CC=CC=C4C3)O
InChI:
InChI=1S/C24H32N6O3/c1-17(31)30-10-7-20(8-11-30)28-23-12-22(26-16-27-23)24(33)25-13-21(32)15-29-9-6-18-4-2-3-5-19(18)14-29/h2-5,12,16,20-21,32H,6-11,13-15H2,1H3,(H,25,33)(H,26,27,28)/t21-/m0/s1
InChIKey:
JLCCNYVTIWRPIZ-NRFANRHFSA-N
Solubility:
DMSO: ≥ 30 mg/mL
Appearance:
White to Yellow Solid
Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms:
GSK-3326595; GSK 3326595; GSK3326595; EPZ015938; EPZ 015938; EPZ-015938; 6-[(1-acetylpiperidin-4-yl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyrimidine-4-carboxamide

Purity: 98%
Smile code: O=C(C1=NC=NC(NC2CCN(C(C)=O)CC2)=C1)NC[C@H](O)CN3CC4=C(C=CC=C4)CC3
MDL Number: MFCD29991177
MolFormula: C24H32N6O3
MolWeight: 452.5493
Available in stock: 8.839

Smile code:
O=C(C1=NC=NC(NC2CCN(C(C)=O)CC2)=C1)NC[C@H](O)CN3CC4=C(C=CC=C4)CC3
MDL Number:
MFCD29991177
Purity :
98%
Available in stock:
18.633 g