Description:
Amonafide is an imide derivative of naphthalic acid. Amonafide intercalates into DNA and inhibits topoisomerase II, resulting in protein-associated strand breaks and impaired DNA and RNA synthesis.
- Molecular Weight:283.33
- Purity:0.98
Molecular Formula:
C16H17N3O2
Canonical SMILES:
CN(C)CCN1C(=O)C2=CC=CC3=CC(=CC(=C32)C1=O)N
InChI:
InChI=1S/C16H17N3O2/c1-18(2)6-7-19-15(20)12-5-3-4-10-8-11(17)9-13(14(10)12)16(19)21/h3-5,8-9H,6-7,17H2,1-2H3
InChIKey:
UPALIKSFLSVKIS-UHFFFAOYSA-N
Solubility:
H <1 (mg/mL)
Appearance:
Light yellow to yellow solid
Application:
Antineoplastic Agents
Synonyms:
Nafidimide; Quinamed; Xanafide Más detalles se encuentran
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