Proveedores de CAS
81129-83-1
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Identificación | CAS |
81129-83-1 | Formula |
C16H25N2NaO5S | EINECS |
279-694-4 |
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14 Proveedores registrados
Simagchem Corporation
P.R.China
Dayang Chem (Hangzhou) Co.,Ltd.
P.R.China
Xingrui Industry Co., Limited
P.R.China
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C16H25N2O5S.Na Molecular Weight: 380.44
Más detalles se encuentran aquí
Shandong Minglang Chemical Co., Ltd
P.R.China
Hangzhou Zhongqi Chem Co., Ltd
P.R.China
Lori Industry Co., Ltd
P.R.China
Skyrun Industrial Co., Ltd.
P.R.China
BOC Sciences
USA
Description: Cilastatin sodium is the sodium salt of cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects. - Molecular Weight:380.43
- Purity:≥99% by HPLC
Molecular Formula: C16H25N2NaO5S Canonical SMILES: CC1(CC1C(=O)NC(=CCCCCSCC(C(=O)O)N)C(=O)[O-])C.[Na+] InChI: InChI=1S/C16H26N2O5S.Na/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21;/h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23);/q;+1/p-1/b12-6-;/t10-,11+;/m1./s1 InChIKey: QXPBTTUOVWMPJN-QBNHLFMHSA-M Synonyms: L 642957; MK 791; L642957; MK791; L-642957; MK-791; [R-[R*,S*-(Z)]]-7-[(2-Amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]-2-heptenoic Acid Monosodium Salt; (2Z)-7-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic Acid Sodium Salt; sodium S-((Z)-6-carboxy-6-((S)-2,2-dimethylcyclopropane-1-carboxamido)hex-5-en-1-yl)-L-cysteinate Más detalles se encuentran aquí
Xiamen Equation Chemical Co.,Ltd
P.R.China
AK Scientific, Inc.
USA
Chemos GmbH & Co. KG
Germany
BuGuCh & Partners
Germany
Santa Cruz Biotechnology, Inc.
USA
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