Description:
Ritonavir is an HIV protease inhibitor. It is often used in a low dose with another protease inhibitor lopinavir.
- Molecular Weight:720.95
- Boiling Point:947.0±65.0 °C at 760 mmHg
- Melting Point:120-122°C
- Purity:≥98%
Molecular Formula:
C37H48N6O5S2
Canonical SMILES:
CC(C)C1=NC(=CS1)CN(C)C(=O)NC(C(C)C)C(=O)NC(CC2=CC=CC=C2)CC(C(CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)O
InChI:
InChI=1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1
InChIKey:
NCDNCNXCDXHOMX-XGKFQTDJSA-N
Solubility:
In Vitro: DMSO: 25 mg/mL (34.68 mM; Need ultrasonic) H2O: < 0.1 mg/mL (insoluble) In Vivo: 1.Add each solvent one by one: 10% DMSO >> 90% corn oil Solubility: 2.5 mg/mL (3.47 mM); Clear solution; Need warming 2.Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline) Solubility: 2.5 mg/mL (3.47 mM); Suspended solution; Need ultrasonic
Appearance:
White Solid
Storage: Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms:
Norvir; ABT-538; A-84538; 538, ABT; ABT 538; ABT-538; ABT538; Abbott 84538 Más detalles se encuentran
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