Description:
Crizotinib is an anti-cancer drug acting as an ALK (anaplastic lymphoma kinase) and ROS1 (c-ros oncogene 1) inhibitor.
- Molecular Weight:450.343
- Boiling Point:599.2±50.0 °C at 760 mmHg
- Melting Point:201-203°C
- Purity:>98%
Molecular Formula:
C21H22Cl2FN5O
Canonical SMILES:
CC(C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N
InChI:
InChI=1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1
InChIKey:
KTEIFNKAUNYNJU-GFCCVEGCSA-N
Solubility:
Insoluble
Appearance:
White Solid
Application:
Antineoplastic Agents
Synonyms:
PF-02341066; PF 02341066; PF02341066 Más detalles se encuentran
aquí