BGC > Buscar Producto >

Molecular Formula: C17H14Cl2F2N2O3
Molecular Weight: 403.2074664
Hazard Symbols: Xi
WGKGermany: 3

Description:
Roflumilast has anti-inflammatory effects and is under development as an orally administered drug for the treatment of inflammatory conditions of the lungs such as asthma, and chronic obstructive pulmonary disease (COPD). While Roflumilast was found to be effective in clinical trials, it produced several dose-limiting side effects including nausea, diarrhoea and headache, and development is continuing in an attempt to minimise the incidence of side effects while retaining clinical efficacy.

• Molecular Weight:403.207
• Boiling Point:430.6±45.0 °C at 760 mmHg
• Melting Point:154-158°C
• Purity:99%

Molecular Formula:
C17H14Cl2F2N2O3
Canonical SMILES:
C1CC1COC2=C(C=CC(=C2)C(=O)NC3=C(C=NC=C3Cl)Cl)OC(F)F
InChI:
InChI=1S/C17H14Cl2F2N2O3/c18-11-6-22-7-12(19)15(11)23-16(24)10-3-4-13(26-17(20)21)14(5-10)25-8-9-1-2-9/h3-7,9,17H,1-2,8H2,(H,22,23,24)
InChIKey:
MNDBXUUTURYVHR-UHFFFAOYSA-N
Solubility:
In vitro: 10 mM in DMSO
Appearance:
White to off-White Solid
Storage: Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms:
BY217; BY-217; BY 217; B 9302-107; B9302-107; B-9302-107; BYK 20869; BYK-20869; BYK20869; Daxas; Daliresp

Purity: 99%
Smile code: O=C(NC1=C(Cl)C=NC=C1Cl)C2=CC=C(OC(F)F)C(OCC3CC3)=C2
MDL Number: MFCD00938270
MolFormula: C17H14Cl2F2N2O3
MolWeight: 403.2100
Available in stock: 311.433

Smile code:
O=C(NC1=C(Cl)C=NC=C1Cl)C2=CC=C(OC(F)F)C(OCC3CC3)=C2
MDL Number:
MFCD00938270
Purity :
99%
Available in stock:
259.801 g