BGC > Produktsuche > U104 | 178606-66-1

Molecular Formula: C13H12FN3O3S
Molecular Weight: 309.3160832
Hazard Symbols: Xi
WGKGermany: 3

Description:
SLC-0111, also known as U-104, MST-104 and NSC 213841, is a potent carbonic anhydrase (CA) inhibitor (Ki values are 4.5, 45.1, 5080 and 9640 nM for CA XII, CA IX, CA I and CA II respectively in MDA-MB-231 cells). U-104 associates with CAIX/CAXII only under hypoxic conditions in vivo, reducing extracellular acidity and resulting in significant inhibition of tumor growth and metastasis in experimental models.

• Molecular Weight:309.31
• Melting Point:242-243 °C

Molecular Formula:
C13H12FN3O3S
Canonical SMILES:
FC1=CC=C(C=C1)NC(NC2=CC=C(C=C2)S(N)(=O)=O)=O
InChI:
1S/C13H12FN3O3S/c14-9-1-3-10(4-2-9)16-13(18)17-11-5-7-12(8-6-11)21(15,19)20/h1-8H,(H2,15,19,20)(H2,16,17,18)
InChIKey:
YJQZNWPYLCNRLP-UHFFFAOYSA-N
Solubility:
DMSO: >15mg/mL
Appearance:
Solid powder
Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms:
4-(3-(4-fluorophenyl)ureido)benzenesulfonamide; SLC-0111; SLC0111; SLC 0111; MST-104; MST-104; MST-104; NSC-213841; NSC213841; NSC 213841; U-104; U104; U 104.