BGC > Produktsuche > Tenofovir disoproxil fumarate | 202138-50-9

Molecular Formula: C19H30N5O10P.C4H4O4
Molecular Weight: 635.51

Description:
Tenofovir Disoproxil Fumarate belongs to a class of antiretroviral drugs, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5'-triphosphate.

• Molecular Weight:635.51
• Boiling Point:642.7ºC at 760 mmHg
• Melting Point:113-115 °C (dec.)
• Purity:>98%

Molecular Formula:
C19H30N5O10P.C4H4O4
Canonical SMILES:
CC(C)OC(=O)OCOP(=O)(COC(C)CN1C=NC2=C(N=CN=C21)N)OCOC(=O)OC(C)C.C(=CC(=O)O)C(=O)O
InChI:
InChI=1S/C19H30N5O10P.C4H4O4/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24;5-3(6)1-2-4(7)8/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22);1-2H,(H,5,6)(H,7,8)/t14-;/m1./s1
InChIKey:
VCMJCVGFSROFHV-PFEQFJNWSA-N
Solubility:
In Vitro: DMSO : ≥ 50 mg/mL (78.68 mM) H2O : 16.67 mg/mL (26.23 mM; Need ultrasonic and warming) In Vivo: 1.Add each solvent one by one: 10% DMSO >> 90% corn oil Solubility: ≥ 2.5 mg/mL (3.93 mM); Clear solution 2.Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline Solubility: ≥ 2.5 mg/mL (3.93 mM); Clear solution 3.Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline) Solubility: ≥ 2.5 mg/mL (3.93 mM); Clear solution
Appearance:
White Solid
Storage: Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms:
GS-1278 Disoproxil Fumarate; GS 1278 Disoproxil Fumarate; GS1278 Disoproxil Fumarate

Purity: 99%
Smile code: [C@@H](C[N]2C1=NC=NC(=C1N=C2)N)(OC[P](OCOC(OC(C)C)=O)(OCOC(OC(C)C)=O)=O)C.O=C(C=CC(O)=O)O
MDL Number: MFCD08141829
MolFormula: C23H34N5O14P
MolWeight: 635.5149
Available in stock: 7665.202

Smile code:
[C@@H](C[N]2C1=NC=NC(=C1N=C2)N)(OC[P](OCOC(OC(C)C)=O)(OCOC(OC(C)C)=O)=O)C.O=C(C=CC(O)=O)O
MDL Number:
MFCD08141829
Purity :
99%
Available in stock:
4928.38 g