Description:
VU-0483605, an isoindol derivative, has been found to be a mGluR1 positive allosteric modulator and probably be effective against schizophrenia. EC50: 356 and 390 nM for rat and human receptors, respectively.
- Molecular Weight:446.67
- Purity:98%
Molecular Formula:
C20H10Cl3N3O3
Canonical SMILES:
C1=CC2=C(C(=C1)Cl)C(=O)N(C2=O)C3=C(C=C(C=C3)NC(=O)C4=C(C=CC=N4)Cl)Cl
InChI:
InChI=1S/C20H10Cl3N3O3/c21-12-4-1-3-11-16(12)20(29)26(19(11)28)15-7-6-10(9-14(15)23)25-18(27)17-13(22)5-2-8-24-17/h1-9H,(H,25,27)
InChIKey:
HJQXPBKPTGWZCF-UHFFFAOYSA-N
Solubility:
DMSO: 50 mM
Appearance:
Powder
Storage: Store in a cool and dry place and at 0 - 4 °C for short term (days to weeks) or -20 °C for long term (months to years).
Synonyms:
CHEMBL3628116; VU0483605, VU-0483605, VU 048360; AOB6248; SYN5042; AOB 6248; SYN 5042; AOB-6248; SYN-5042; 3-chloro-N-[3-chloro-4-(4-chloro-1,3-dioxoisoindol-2-yl)phenyl]pyridine-2-carboxamide Weitere Informationen finden Sie
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