BGC > Produktsuche > BAM 15 | 210302-17-3

Description:
BAM 15 is a novel mitochondrial protonophore uncoupler that uncouples oxidative phosphorylation in L6 myoblast mitochondria in vitro (EC50 = 270 nM). BAM 15 cannot depolarize the plasma membrane, and protects mice from acute renal ischemic-reperfusion injury. BAM 15 has the potential to treat obesity, Parkinson's disease, and aging.

• Molecular Weight:340.29
• Boiling Point:421.7±55.0 °C at 760 mmHg
• Purity:≥98% by HPLC

Molecular Formula:
C16H10F2N6O
Canonical SMILES:
C1=CC=C(C(=C1)NC2=NC3=NON=C3N=C2NC4=CC=CC=C4F)F
InChI:
InChI=1S/C16H10F2N6O/c17-9-5-1-3-7-11(9)19-13-14(20-12-8-4-2-6-10(12)18)22-16-15(21-13)23-25-24-16/h1-8H,(H,19,21,23)(H,20,22,24)
InChIKey:
OEGJBRZAJRPPHL-UHFFFAOYSA-N
Synonyms:
BAM15; BAM-15; N5,N6-bis(2-Fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine; N-[6-(2-Fluoroanilino)[1,2,5]oxadiazolo[3,4-b]pyrazin-5-yl]-N-(2-fluorophenyl)amine