BGC > Produktsuche > N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine | 315703-52-7

Molecular Formula: C19H18N4OS
Molecular Weight: 350.444
Hazard Symbols: Xn
WGKGermany: 3

Description:
JK-184 is a potent downstream hedgehog (Hh) signaling antagonist that functions by alcohol dehydrogenase 7 (Adh7) inhibition, preventing Gli-dependent transcriptional activity (IC50 = 30 nM). Hedgehog signaling plays a key role in a wide variety of developmental processes as well as cancer progression. JK-184 exhibits antiproliferative activity.

• Molecular Weight:350.44
• Purity:98%

Molecular Formula:
C19H18N4OS
Appearance:
Light pink color
Application:
Differentiation
Synonyms:
JK184; JK 184