BGC > Produktsuche > Glycyrrhizic acid | 1405-86-3

Appearance	White crystalline powder,odorless,with special sweetness
Identification	Positive reaction
Assay	≥ 95%
Loss on drying	≤ 6.0%
Residue on ignition	≤ 0.2%
As	≤ 2PPM
Heavy metals	≤ 20PPM
Standard	Technical grade
Capacity	50MT/month
Loading port	Shanghai
Package	25kg/drum or according to the customers’ demand
Storage	Stored in the dry and ventilated inside storeroom, prevent direct sunlight, slightly pile and put down

Appearance	White crystalline powder,odorless,with special sweetness
Identification	Positive reaction
Assay	≥ 95%
Loss on drying	≤ 6.0%
Residue on ignition	≤ 0.2%
As	≤ 2PPM
Heavy metals	≤ 20PPM
Standard	Technical grade
Content	95%
Capacity	50MT/month
Loading port	Shanghai
Package	25kg/drum or according to the customers’ demand
Storage	Stored in the dry and ventilated inside storeroom, prevent direct sunlight, slightly pile and put down

Molecular Formula: C42H62O16
Molecular Weight: 822.93
WGKGermany: 3
HS Code: 29389090

EINECS:215-785-7
Molecular formula:C42H62O16

Description:
Glycyrrhizin (Glycyrrhizic Acid) is a widely used anti-inflammatory agent isolated from the licorice root. It has anti-tumor, antiviral ,antiallergic, anti-inflammatory, immunoregulatory,anti-diabetic activities. Glycyrrhizic acid also can be used in cosmetics material.

• Molecular Weight:822.93
• Boiling Point:971.4±65.0°C at 760 mmHg
• Melting Point:>186°C (dec.)
• Purity:>98%

Molecular Formula:
C42H62O16
Canonical SMILES:
CC1(C2CCC3(C(C2(CCC1OC4C(C(C(C(O4)C(=O)O)O)O)OC5C(C(C(C(O5)C(=O)O)O)O)O)C)C(=O)C=C6C3(CCC7(C6CC(CC7)(C)C(=O)O)C)C)C)C
InChI:
InChI=1S/C42H62O16/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54)/t19-,21-,22-,23-,24-,25-,26-,27+,28-,29-,30+,31+,34-,35-,38+,39-,40-,41+,42+/m0/s1
InChIKey:
LPLVUJXQOOQHMX-QWBHMCJMSA-N
Solubility:
Soluble in DMSO (Slightly), Ethanol (Slightly), Methanol (Sparingly), Pyridine (Slightly)
Appearance:
White to Light Yellow Solid
Storage: Store at 2-8°C, under inert atmosphere
Synonyms:
Glycyrrhizin; Glycyrrhizinic acid; Glycyron; Glycyrrhetinic acid glycoside; NSC 2800; NSC-234419; (3β)-30-Hydroxy-11,30-dioxoolean-12-en-3-yl 2-O-β-D-glucopyranuronosyl-α-D-glucopyranosiduronic acid; (3β,20β)-20-Carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-D-Glucopyranuronosyl-α-D-glucopyranosiduronic Acid; 18β-Glycyrrhizic Acid; 18β-Glycyrrhizinic Acid; Potenlini; β-Glycyrrhizin

Glycyrrhizic acid is extracted from the roots of the licorice plant; licorice. It is a triterpene glycoside with glycyrrhetinic acid and has a wide range of pharmacological and biological activities. When extracted from plants, it can be obtained in the form of ammonium glycyrrhizinate and monoammonium glycyrrhizinate. Glycyrrhizin has been developed as a liver-protective drug for chronic hepatitis cases in Japan and China. Since January 2014, glycyrrhizic acid as a part of licorice extract has been approved by the FDA as an existing food sweetener. It has been approved by Health Canada for over-the-counter products, but all products are currently in a post-market cancellation status.
Glycyrrhizin is a saponin-like compound that provides licorice (Glycyrrhiza) with the main sweetness and has potential immunomodulatory, anti-inflammatory, liver and neuroprotective and anti-tumor activities. Glycyrrhizin regulates certain enzymes involved in inflammation and oxidative stress, and down-regulates certain pro-inflammatory mediators, thereby preventing inflammation and reactive oxygen species (ROS)-induced damage. Glycerin may also inhibit the growth of susceptible tumor cells.

NCI Thesaurus (NCIt)
A widely used anti-inflammatory agent isolated from licorice root. It is metabolized to glycyrrhetinic acid, which inhibits 11-beta-hydroxysteroid dehydrogenase and other enzymes involved in corticosteroid metabolism. Therefore, glycyrrhizic acid is the main and sweet component of licorice. It has been studied for its ability to cause high-molecular corticosteroid poisoning, accompanied by sodium retention and potassium loss, edema, elevated blood pressure, and renin-angiotensin-aldosterone system. inhibition.