Lieferanten für CAS
796967-16-3
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Daten | CAS |
796967-16-3 | Formula |
C21H18FN5O |
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9 Registerierte Lieferanten
Capot Chemical Co., Ltd.
P.R.China
Weitere Informationen finden Sie hier
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C21H18FN5O Molecular Weight: 375.405
Aea.ltd
P.R.China
Hangzhou Zhongqi Chem Co., Ltd
P.R.China
Hangzhou Lingrui Chemical Co., Ltd.
P.R.China
Skyrun Industrial Co., Ltd.
P.R.China
BOC Sciences
USA
Description: Description of Linifanib: Linifanib is an orally bioavailable, small-molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Linifanib inhibits members of the vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) receptor families; it exhibits much less activity against unrelated RTKs, soluble tyrosine kinases, or serine/threonine kinases. This agent does not have a general antiproliferative effect due to its high dose requirement. However, linifanib may exhibit potent antiproliferative and apoptotic effects on tumor cells whose proliferation is dependent on mutant kinases, such as fms-related tyrosine kinase receptor-3 (FLT3). Molecular Formula: C21H18FN5O Canonical SMILES: CC1=CC(=C(C=C1)F)NC(=O)NC2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N InChI: InChI=1S/C21H18FN5O/c1-12-5-10-16(22)18(11-12)25-21(28)24-14-8-6-13(7-9-14)15-3-2-4-17-19(15)20(23)27-26-17/h2-11H,1H3,(H3,23,26,27)(H2,24,25,28) InChIKey: MPVGZUGXCQEXTM-UHFFFAOYSA-N Synonyms: ABT869; ABT 869; ABT-869; Linifanib Weitere Informationen finden Sie hier
CM Fine Chemicals
Switzerland
Santa Cruz Biotechnology, Inc.
USA
Detaillierte Informationen über die Lieferanten von
Linifanib
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