BGC > Produktsuche > Mitapivat | 1260075-17-9

Molecular Formula: C24H26N4O3S
Molecular Weight: 450.55324

Description:
Activator of pyruvate kinase isoenzyme M2 (PKM2), an enzyme involved in glycolysis. Since all tumor cells exclusively express the embryonic M2 isoform of PK, it is hypothesized that PKM2 is a potential target for cancer therapy. Modulation of PKM2 might also be effective in the treatment of obesity, diabetes, autoimmune conditions, and antiproliferation-dependent diseases.

• Molecular Weight:450.55
• Purity:>98%

Molecular Formula:
C24H26N4O3S
Canonical SMILES:
C1CC1CN2CCN(CC2)C(=O)C3=CC=C(C=C3)NS(=O)(=O)C4=CC=CC5=C4N=CC=C5
InChI:
InChI=1S/C24H26N4O3S/c29-24(28-15-13-27(14-16-28)17-18-6-7-18)20-8-10-21(11-9-20)26-32(30,31)22-5-1-3-19-4-2-12-25-23(19)22/h1-5,8-12,18,26H,6-7,13-17H2
InChIKey:
XAYGBKHKBBXDAK-UHFFFAOYSA-N
Synonyms:
PKR-IN-1; PKM2 activator 1020; PKM2 activator; Mitapivat.